Ask Vivomed’s Pharmacist – Prohibited Substances in Sport & What you need to know

Ask Vivomed‘s Pharmacist – Prohibited Substances in Sport & What you need to know

Doping in sport has relevance as far back as competitions in ancient Greece to today’s multi-billion-pound sports industry. A win at all cost nature has fueled doping in both amateur & professional athletes in their quest for victory.

The Prohibited List

The prohibited list is divided into three different sections; substances & methods banned in competition, out of competition & those banned in specific sports.

The prohibited list is integral to the anti-doping movement and enables global harmonisation across all sports. The prohibited list is published on an annual basis and can be obtained through the World Anti-Doping Agency (WADA) website. Its important to mention that substances can be added to the list at any time meaning athletes should be vigilant to ensure any medications they are taking are within the parameters of the anti-doping code. A substance or method will be considered for the prohibited list if two of the following criteria is fulfilled;
• Potential to enhance in performance
• Represents an actual or potential health risk to the given athlete
• Violates the morals & ethics of the sport

Those substances which may mask the use of a prohibited substance or method are also strictly prohibited and would result in an Anti-Doping Rule Violation (ADRV)

Prohibited Substances

S0– Non-Approved Substances
S1– Anabolic Agents e.g. Stanozolol, 1-Testosterone

Ask the Vivomed Pharmacist- Prohibited Substances in Sport & What you need to know
Ask the Vivomed Pharmacist- Prohibited Substances in Sport & What you need to know

S2– Peptide Hormones, Growth Factors, Related Substances & Mimetics e.g. EPO, IGF-1
S3– Beta-2 Agonists e.g. Terbutaline, Formoterol
S4– Hormone & Metabolic Modulators e.g. Clomifene, Tamoxifen
S5– Diuretics & Masking Agents e.g. Probenecid, Spirnolactone
S6– Stimulants e.g. Modafinil, Lisdexamfetamine
S7-Narcotics e.g. Oxycodone, Morphine
S8-Cannabinoids e.g. Cannabis, Marijuana
S9-Glucocorticoids e.g. Prednisone, Betamethasone

Prohibited Methods

M1– Manipulation of Blood & Blood Components
M2– Chemical & Physical Manipulation
M3– Gene Doping

Therapeutic Use Exemption (TUE)

An athlete may be issued a TUE to use a prohibited substance should they satisfy the following conditions;
a) To treat a medical condition
b) The prohibited substance is unlikely to produce an enhancement of performance
c) There are no suitable alternatives
d) The need for the prohibited substance is not a consequence of previous use of a prohibited substance.

Examples of TUE’s include the prescribing of Salbutamol inhalers for conditions such as exercise induced asthma. Its also worth noting that there are strict dosage guidelines which must be adhered to. The maximum dosage of inhaled salbutamol is 1600mcg over a given 24-hour period (equivalent to 16*100mcg puffs), not exceeding 800mcg over 12 hours. A urine sample reading over 1000ng/mL would result in an Adverse Analytical Finding (AAF), unless the athlete is able to prove otherwise through a controlled pharmacokinetic study.

Over the Counter (OTC) Medications

Athletes should be aware that many common OTC medications contain substances which are present on the prohibited substance list. It is the given athlete’s responsibility to ensure they check ANY medication before use. Examples include cold & flu products containing the banned stimulant “Pseudoephedrine” like Sudafed & Lemsip. Other stimulants such as caffeine which is found in tea & coffee is included in the 2018 monitoring programme but not considered a prohibited substance.

Dietary Supplements

Special care should be exercised using diet supplementation, ensuring they contain no traces of prohibited substances such as fat burners & anabolic steroids. You can check if your supplement is certified by using the informed sport website database CLICK HERE .

Ask the Vivomed Pharmacist- Prohibited Substances in Sport & What you need to know
Ask the Vivomed Pharmacist- Prohibited Substances in Sport & What you need to know

Useful Links

Informed Sport Database- http://informed-sport.com/

World Anti Doping Agency (WADA)- https://www.wada-ama.org/

 

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